Losing hope is not so bad. There's something worse: losing hope and hiding it from yourself.
We may know ourselves, and yet even with all the efforts we make, we do not know ourselves. We know our fellowman, and yet we do not know him, because we are not a thing, and our fellowman is not a thing. The further we reach into the depths of our being, on someone else's being, the more the goal of knowledge eludes us.